(EMAILWIRE.COM, February 24, 2013 ) San Francisco, CA -- A new and shorter treatment for skin infections of the bacterial variety has proven to be as effective as the longer versions of treatment, according to new studies.
These infections, which include cellulitis and other wound infections, can be life threatening, noted one expert not connected to the study, Dr. Michele Green, a dermatologist at Lenox Hill Hospital, in New York City. Because so many of these infections have become antibiotic-resistant, the development of a novel antibiotic which is effective is very important, she added.
The new phase 3 clinical trial had included 667 adult patients in North America, Europe, and Latin America, who had received either 200 milligram pills of tedizolid for a week or 600 milligram pills twice as often for 10 days.
The drugs proved to show similar levels of effectiveness after three days, as well as after 11 days, according to the study that will be published in an issue of the Journal of the American Medical Association.
The side effects, most of which were mild or moderate, occurred in just over 40% of patients taking tedizolid, a 43% of those taking linezolid. The rates for serious side effects were low, and did not differ much between groups.
Dr. Phillippe Prokcimer, of Trius Therapeutics Inc., San Diego lead the study. The company is the creator of tedizolid and funded the project.
According to Green, the study suggests that tedizolid is a worthwhile alternative to older drugs. This holds true especially for MRSA, which is a growing problem, due to antibiotic resistance and the continued use of prolonged antibiotics.
Dr. Scott Gorenstein, who is an expert in wound healing therapies at Winthrop-University Hospital in Mineola, N.Y. Stated that it is important to find shorter alternatives to current treatment to reduce the cause of antibiotic-resistant complications.
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