Y Combinator Winter 2012 graduate Data Nitro (formerly known as IronSpread) has a simple proposition: it enables you to to use the popular programming language Python in Microsoft Excel. The plugin is free for individual non-commercial and enterprises will pay for the privilege. So far it’s only available for the Excel 2007 and 2010 for Windows. The company has no plans to support OSX.
The good news: You can still use all your old VBA scripts, Data Nitro won’t stop them from working. Plus you can use existing Python libraries. The bad news: anyone you send the spreadsheet to will need to install the plugin in order to run the Python script.