Safeguard to Present at The Wall Street Analyst Forum's 17th Annual Analyst Conference

Safeguard Scientifics, Inc. (NYSE:SFE), which builds value in high-growth, revenue-stage information technology and life sciences companies, today announced Peter J. Boni, President and Chief Executive Officer, will present at The Wall Street Analyst Forum's 17th Annual Analyst Conference on Wednesday, September 27, 2006 at 11:10am EDT. Mr. Boni will offer an overview of Safeguard, its growth strategy and value proposition to institutional investors. A breakout session for investors who have additional questions will immediately follow Mr. Boni's presentation. The event will be held at The Princeton Club, New York City, New York.

The Wall Street Analyst Forum will provide a live web cast of the presentation with accompanying slides. Interested parties may access the web cast via Safeguard's website, www.safeguard.com under the Investors section.

About Safeguard

Safeguard Scientifics, Inc. (NYSE:SFE) builds value in high-growth, revenue-stage information technology and life sciences businesses. We provide growth capital as well as a range of strategic, operational and management resources to our partner companies. Safeguard participates in expansion financings, corporate spin-outs, management buyouts, recapitalizations, industry consolidations and early-stage financings. For more information about Safeguard and its strategy, visit www.safeguard.com.

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