At the 52nd ENC, Bruker today announced the receipt of two separate orders for novel 395 GHz Solid State DNP-NMR systems that utilize Dynamic Nuclear Polarization (DNP) in order to significantly enhance the sensitivity of solid state NMR experiments. Based on Bruker’s proven and unique 263 GHz Solid State DNP-NMR systems, and in addition to the 527 GHz ultra-high field system in development at Bruker for the University of Utrecht, The Netherlands (announced in December 2010), this new 395 GHz DNP-NMR instrument augments the field strength choices for commercial, high-performance DNP-NMR equipment.
263 GHz Avance Solid-State DNP-NMR spectrometer (Photo: Business Wire)
The first 395 GHz system will be installed at Bruker’s US applications facility in Billerica, MA to be available for continued developments, applied research and customer demonstrations. DNP–enhanced solid state NMR has found great applications in research on biological solids, such as the important field of membrane proteins. Recently, solid state DNP-NMR has also been shown to be a unique tool in materials research, and even as a means to look at surfaces.
The early scientific successes in DNP-NMR have resulted in successful grant applications in several countries for its use in biological research:
- Prof. Vladimir Ladizhansky at the University of Guelph (Guelph, Ontario, Canada) will receive the first commercial 395 GHz DNP-NMR spectrometer.
- Prof. Christian Griesinger has placed an order for a 395 GHz system for the Max Planck Institute for Biophysical Chemistry in Goettingen, Germany.
Dynamic Nuclear Polarization significantly enhances the sensitivity of solid state NMR by transferring polarization from the electron spins to the nuclear spins. The solid state DNP-NMR technology commercialized by Bruker finds its origins in the pioneering work of Professors Robert Griffin and Richard Temkin at MIT. The 395 GHz Solid State DNP-NMR system utilizes a novel 395 GHz gyrotron as the high power microwave source, Bruker’s Ascend™ 600 MHz 89 mm widebore superconducting magnet, and the ultra-fast Avance™ III electronics for the NMR detection.
Dr. Werner Maas, President of Bruker BioSpin, commented: “We are extremely pleased with these first orders for our novel 395 GHz DNP-NMR systems. The unique research that is ongoing, enabled by the sensitivity breakthrough offered via the DNP enhancement, is creating a paradigm shift in solid state NMR. We are confident that the adoption of this technology by these outstanding researchers will lead to very exciting new science in biological systems.”
About Bruker Corporation
Bruker Corporation is a leading provider of high-performance scientific instruments and solutions for molecular and materials research, as well as for industrial and applied analysis. For more information about Bruker Corporation, please visit http://www.bruker.com
For more information on Solid State DNP-NMR systems, please visit www.bruker.com/dnp
For more information on the 52nd ENC, please visit: www.enc-conference.org
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